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The NanoKnife® System delivers a non-thermal approach to localized ablation through its unique Irreversible Electroporation (IRE) technology. By using high-voltage electrical pulses to create permanent nanopores in targeted cell membranes, the system induces controlled cell death while preserving critical surrounding structures.
This mechanism enables precise and customizable ablation zones using multiple electrode configurations, allowing treatment to be tailored to patient anatomy. Ablation margins are sharply defined and can be visualized in real time using ultrasound, supporting accurate and confident therapy delivery.
Designed to support precision, preservation, and versatility, the NanoKnife System enables an organ-sparing approach that maintains tissue structure and supports post-procedure tissue regeneration.
Precision
Multiple electrode configurations allow physicians to sculpt and control the ablation zone, providing precise treatment margins and confident coverage.
Preservation
The non-thermal delivery of energy preserves tissue architecture and the extracellular matrix, supporting post-ablation histological and functional tissue regeneration while sparing vital structures.
Versatility
The system can be used across all segments of an organ, with electrodes placed near critical structures to support personalized treatment based on patient anatomy.
This mechanism enables precise and customizable ablation zones using multiple electrode configurations, allowing treatment to be tailored to patient anatomy. Ablation margins are sharply defined and can be visualized in real time using ultrasound, supporting accurate and confident therapy delivery.
Designed to support precision, preservation, and versatility, the NanoKnife System enables an organ-sparing approach that maintains tissue structure and supports post-procedure tissue regeneration.
Precision
Multiple electrode configurations allow physicians to sculpt and control the ablation zone, providing precise treatment margins and confident coverage.
Preservation
The non-thermal delivery of energy preserves tissue architecture and the extracellular matrix, supporting post-ablation histological and functional tissue regeneration while sparing vital structures.
Versatility
The system can be used across all segments of an organ, with electrodes placed near critical structures to support personalized treatment based on patient anatomy.
